When something doesn’t feel right, let your veterinarian know

While the likelihood of arthritis increases with age, maintaining your horse’s joints with Adequan® i.m. (polysulfated glycosaminoglycan) can help extend your partnership and even help retired horses live better. Talk to your veterinarian to see if Adequan i.m. is right for your horse.


FDA-approved to treat arthritis, not just its symptoms

Healthy joints help maintain well-being, regardless of whether your horse walks the pasture, is a first-time Western pleasure winner or a Grand Prix competitor turned steadfast companion.

As the only FDA-approved treatment for degenerative joint disease (DJD) in horses that helps restore cartilage, Adequan i.m. actually treats the disease, not just its symptoms.1,2,4 For over 30 years, veterinarians have given Adequan i.m. to help horses of every discipline and level enjoy greater mobility over their lifetimes.1,3,4

Know your options

Which joint health products can you trust to keep your horse moving?

This is not a complete list of all products available.

Adequan® i.m. is recommended for the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses.

There are no known contraindications to the use of intramuscular Polysulfated Glycosaminoglycan (PSGAG). Studies have not been conducted to establish safety in breeding horses. WARNING: Do not use in horses intended for human consumption. Not for use in humans. Keep this and all medications out of the reach of children. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For full prescribing information, click here.

Start with it.
Stay with it.®

If your veterinarian observes the early signs of arthritis in your horse, they may recommend Adequan i.m. to help slow its effects and prevent further damage. Following the recommended dosing schedule ensures maximum efficacy and safety.

After the first treatment, you and your veterinarian should continue to watch your horse’s joint health and mobility. Your veterinarian may recommend repeating the schedule shown as needed if the signs of arthritis return.

Dosing Example

Lance got his freedom back

"Lance is 6 years old and has arthritis. His course of Adequan i.m. (polysulfated glycosaminoglycan) really made a remarkable difference in his freedom of movement and level of comfort in that movement. We gave him a break from gymnastics while on the medication and will revisit the situation as needed or probably at the 6-month point."

Arthur Vann

Horse Owner
Testimonial used with permission.

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  1. Kim DY, Taylor HW, Moore RM, Paulsen DB, Cho DY. Articular chondrocyte apoptosis in equine osteoarthritis. The Veterinary Journal 2003; 166: 52-57.
  2. McIlwraith CW, Frisbie DD, Kawcak CE, van Weeren PR. Joint Disease in the Horse. St. Louis, MO: Elsevier, 2016; 33-48.
  3. Burba DJ, Collier MA, DeBault LE, Hanson-Painton O, Thompson HC, Holder CL: In vivo kinetic study on uptake and distribution of intramuscular tritium-labeled polysulfated glycosaminoglycan in equine body fluid compartments and articular cartilage in an osteochondral defect model. J Equine Vet Sci 1993; 13: 696-703.
  4. Adequan® i.m. (polysulfated glycosaminoglycan), Package Insert. American Regent, Inc.

Advancing joint care for dogs & horses

For more than 30 years, veterinarians have relied on the American Regent Animal Health family of products to provide solutions that help support joint health in their patients. Our mission is to champion the long-term well-being and mobility of animals, from top athletes to family companions.